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Genomic deletions and mutations resulting in the loss of eight genes reduce the in vivo replication capacity of Meleagrid herpesvirus 1.

Virus genes - 1 Aug 2015

Mahony Timothy J, Hall Robyn N, Walkden-Brown Stephen, Meers Joanne, Gravel Jennifer L, West Lani, Hardy Vanessa, Islam A F M Fakhrul, Fowler Elizabeth V, Mitter Neena

Abstract excerpt

Meleagrid herpesvirus 1 (MeHV-1 or turkey herpesvirus) has been widely used as a vaccine in commercial poultry. Initially, these vaccine applications were for the prevention of Marek's disease resulting from Gallid herpesvirus 2 infections, while more recently MeHV-1 has been used as recombinant vector for other poultry infections. The construction of herpesvirus infectious clones that permit propagation and...

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PMID: 26149791
DOI: 10.1007/s11262-015-1216-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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