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Article

Protective effects of angiotensin-converting enzyme I/I and matrix metalloproteinase-3 6A/6A polymorphisms on dilatative pathology within the ascending thoracic aorta.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery - 1 Jul 2011

Lesauskaite Vaiva, Sinkunaite-Marsalkiene Giedre, Tamosiunas Abdonas, Benetis Rimantas

Abstract excerpt

OBJECTIVE: Activation of matrix metalloproteinases and the renin/angiotensin signaling pathways is under investigation with regard to their potential pathogenesis in dilatative pathology of the aorta. The purpose of this study was to explore matrix metalloproteinase-3 5A/6A and angiotensin-converting enzyme I/D polymorphisms as predisposing factors to dilatative pathology of the aorta. METHODS: We studied 107...

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Share to Aortic Aneurysm, Thoracic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aortic Dissection

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Share to Peptidyl-Dipeptidase A

Share to Polymorphism, Genetic

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Source

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Identifiers

PMID: 21111627
DOI: 10.1016/j.ejcts.2010.10.014
PMCID: PMC3968396

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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