Article

Distinct transcriptomic patterns in bicuspid aortic valve aortopathy suggest a unique mechanism of ascending aortic aneurysm progression

2026-05-22

Abstract excerpt

<h4>Objective</h4> To compare RNA-sequencing-derived transcriptomic profiles of thoracic aortic aneurysm tissue from individuals with bicuspid versus trileaflet aortic valves. <h4>Methods</h4> Human ascending aortic tissue was collected from patients undergoing cardiac surgery at a single institution between January 2021 and December 2022 with bicuspid aortic valves (BAV) and trileaflet aortic valves (TAV) with...

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Literature Corpus work: cb5de2d7-f516-50a6-962a-6ce0184e1037
DOI: 10.64898/2026.05.19.26353631

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