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Article

Impaired splicing of fibronectin is associated with thoracic aortic aneurysm formation in patients with bicuspid aortic valve.

Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2011

Paloschi Valentina, Kurtovic Sanela, Folkersen Lasse, Gomez Delphine, Wågsäter Dick, Roy Joy, Petrini Johan, Eriksson Maria J, Caidahl Kenneth, Hamsten Anders, Liska Jan, Michel Jean-Baptiste, Franco-Cereceda Anders, Eriksson Per

Abstract excerpt

OBJECTIVE: Thoracic aortic aneurysm is a common complication in patients with bicuspid aortic valve (BAV). Alternatively spliced extra domain A (EDA) of fibronectin (FN) has an essential role in tissue repair. Here we analyze the expression of FN spliceforms in dilated and nondilated ascending ao...

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Source

Identifiers

PMID: 21148425
DOI: 10.1161/ATVBAHA.110.218461

Genes

EDA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21148425-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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