Article
Alternative splicing is an efficient mechanism for the generation of protein diversity: contractile protein genes as a model system.
Advances in enzyme regulation - 1 Jan 1991
Nadal-Ginard B, Smith C W, Patton J G, Breitbart R E
Abstract excerpt
Alternative splicing has emerged in recent years as a widespread device for regulating gene expression and generating protein diversity. Its analysis has provided some mechanistic understanding of this form of gene regulation and, in addition, has provided new insights into some fundamental aspects of splicing. This mode of regulation is particularly prevalent in muscle cells, where genes such as troponin T are...
Topics
- Animals
- Contractile Proteins
- Exons
- Gene Expression Regulation
- Genetic Variation
- Introns
- Models, Genetic
- RNA Splicing
- RNA, Messenger
- Tropomyosin
- Troponin