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Article

Investigating population stratification and admixture using eigenanalysis of dense genotypes.

Heredity - 1 Oct 2011

Shriner D

Abstract excerpt

Principal components analysis of genetic data is used to avoid inflation in type I error rates in association testing due to population stratification by covariate adjustment using the top eigenvectors and to estimate cluster or group membership independent of self-reported or ethnic identities. Eigendecomposition transforms correlated variables into an equal number of uncorrelated variables. Numerous stopping...

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Identifiers

PMID: 21448230
DOI: 10.1038/hdy.2011.26
PMCID: PMC3128175

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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