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Article

Fast model-based estimation of ancestry in unrelated individuals.

Genome research - 1 Sept 2009

Alexander David H, Novembre John, Lange Kenneth

Abstract excerpt

Population stratification has long been recognized as a confounding factor in genetic association studies. Estimated ancestries, derived from multi-locus genotype data, can be used to perform a statistical correction for population stratification. One popular technique for estimation of ancestry is the model-based approach embodied by the widely applied program structure. Another approach, implemented in the...

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PMID: 19648217
DOI: 10.1101/gr.094052.109
PMCID: PMC2752134

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