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CpG-island methylation study of liver fluke-related cholangiocarcinoma

29 Mar 2011

Abstract excerpt

BACKGROUND: Genetic changes have been widely reported in association with cholangiocarcinoma (CCA), while epigenetic changes are poorly characterised. We aimed to further evaluate CpG-island hypermethylation in CCA at candidate loci, which may have potential as diagnostic or prognostic biomarkers. METHODS: We analysed methylation of 26 CpG-islands in 102 liver fluke related-CCA and 29 adjacent normal samples...

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Share to Cholangiocarcinoma and Gallbladder Cancer Studies
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PMID: 21448164
DOI: 10.1038/bjc.2011.102

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