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Article

Genetics of Opisthorchis viverrini-related cholangiocarcinoma.

Current opinion in gastroenterology - 1 May 2015

Jusakul Apinya, Kongpetch Sarinya, Teh Bin Tean

Abstract excerpt

PURPOSE OF REVIEW: We review the genetic, epigenetic and transcriptional landscape of liver fluke (Opisthorchis viverrini, Ov)-related cholangiocarcinoma (CCA). Its distinct alterations, as compared with non-Ov-related CCA may help shed light on its underlying molecular mechanisms. RECENT FINDINGS: Recent whole-exome and targeted sequencing not only confirmed frequent mutations in known CCA-related genes...

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Topics

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Share to Bile Duct Neoplasms
Share to Cholangiocarcinoma
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Receptors, Immunologic

Share to Sequence Analysis, DNA

Share to Transcriptional Activation

Source

Identifiers

PMID: 25693006
DOI: 10.1097/MOG.0000000000000162

Genes

IDH1
KRAS
BAP1
GNAS
PEG3
RNF43
ROBO2
SMAD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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