Article

Liquid Biopsy in Cholestatic Liver Disease Using Hepatocyte-Specific Methylation Markers

2021-02-19

Abstract excerpt

<h4>Background: </h4> Quantification of circulating organ-specific cell-free DNA (cfDNA) provides a sensitive measure of ongoing cell death that could benefit evaluation of the cholestatic liver diseases primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), which lack reliable non-invasive biomarkers. Our goal in this pilot study was to determine whether liver-specific cfDNA levels are increa...

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Literature Corpus work: d00249bf-c7b8-556b-bdb9-3c7ecf374ce4
DOI: 10.21203/rs.3.rs-209005/v1

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