Article
Association of CLU gene polymorphism with Parkinson's disease in the Chinese Han population.
The journal of gene medicine - 1 Feb 2021
Lin Yuwan, Lu Lin, Zhou Miaomiao, Liu HanQun, Ye Panghai, Zhang Wenlong, Qiu Jiewen, Zhang Zhiling, Yang Xinling, Ding Liuyan, Guo Wenyuan, Mo Mingshu, Zhu Xiaoqin, Zhang Xiaokang, Chen Xiang, Xu Pingyi
Abstract excerpt
BACKGROUND: Clusterin (CLU) plays important role in the pathology of neurodegenerative disorders. Recently, a genetic variant of CLU rs9331896 has been reported as a risk estimate for Alzheimer's disease (AD). However, the association between this variant and the risk of Parkinson's disease (PD) in the Chinese Han population remains elusive. METHODS: We sequenced CLU rs9331896 in 353 PD patients and 326...
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