Article
Surface expression of mutated subunits of the high affinity mast cell receptor for IgE.
The Journal of biological chemistry - 15 Sept 1990
Varin-Blank N, Metzger H
Abstract excerpt
The mast cell receptor with high affinity for IgE consists of four transmembrane polypeptides which are held together by detergent-sensitive interactions: an IgE-binding alpha chain, a single beta chain, and a disulfide-linked dimer of gamma chains. Now that the cDNAs that code for each of the su...
Topics
- Amino Acid Sequence
- Animals
- Antigens, Differentiation, B-Lymphocyte
- Base Sequence
- Cell Line
- Cell Membrane
- Chimera
- Cloning, Molecular
- Gene Expression
- Humans
- Immunoglobulin E
- Macromolecular Substances
- Mast Cells
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Rats
- Receptors, Fc