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Article

Surface expression of mutated subunits of the high affinity mast cell receptor for IgE.

The Journal of biological chemistry - 15 Sept 1990

Varin-Blank N, Metzger H

Abstract excerpt

The mast cell receptor with high affinity for IgE consists of four transmembrane polypeptides which are held together by detergent-sensitive interactions: an IgE-binding alpha chain, a single beta chain, and a disulfide-linked dimer of gamma chains. Now that the cDNAs that code for each of the subunits have been isolated, it should be possible to probe by site-specific mutations, which portions of the receptor...

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PMID: 2144288

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