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Article

Exon Skipping of FcεRIβ for Allergic Diseases.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Arthur Greer K, Cruse Glenn

Abstract excerpt

Mast cells are key effector cells in allergic inflammation and consequently are ideal targets for new therapeutics. The high-affinity IgE receptor complex, FcεRI, plays a critical role in mast cell and basophil activation by allergens to drive the immediate allergic inflammatory response. The β subunit of FcεRI is critical for trafficking the FcεRI complex to the cell membrane and amplifies the FcεRI signaling...

Read the complete abstract on PubMed

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Share to Cell Degranulation
Share to Hypersensitivity
Share to Mast Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Anaphylaxis

Share to Calcium Signaling

Share to Oligonucleotides, Antisense

Share to Receptors, IgE

Share to RNA Splicing

Source

Identifiers

PMID: 30171564
DOI: 10.1007/978-1-4939-8651-4_33

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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