Article
Effects of subunit mutation on the localization to coated pits and internalization of cross-linked IgE-receptor complexes.
Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 1993
Mao S Y, Pfeiffer J R, Oliver J M, Metzger H
Abstract excerpt
IgE receptors of mast cells, Fc epsilon RI, localize to coated pits and internalize after cross-linking. We investigated whether any one of the receptor's four distinctive cytoplasmic domains regulates these phenomena. COS cells, which lack Fc epsilon RI entirely, and P815 mouse mastocytoma cells...
Topics
- Amino Acid Sequence
- Animals
- Cell Line
- Coated Pits, Cell-Membrane
- Endocytosis
- Mast-Cell Sarcoma
- Mice
- Microscopy, Electron
- Molecular Sequence Data
- Mutation
- Rabbits
- Rats
- Receptors, IgE
- Transfection
- Tumor Cells, Cultured