Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of subunit mutation on the localization to coated pits and internalization of cross-linked IgE-receptor complexes.

Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 1993

Mao S Y, Pfeiffer J R, Oliver J M, Metzger H

Abstract excerpt

IgE receptors of mast cells, Fc epsilon RI, localize to coated pits and internalize after cross-linking. We investigated whether any one of the receptor's four distinctive cytoplasmic domains regulates these phenomena. COS cells, which lack Fc epsilon RI entirely, and P815 mouse mastocytoma cells that lack the alpha and beta subunits of the tetrameric Fc epsilon RI (alpha beta gamma 2), were transfected with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Cell Line
Share to Mice

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Transfection

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 8360490

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of subunit mutation on the localization to coated pits and internalization of cross-linked IgE-receptor complexes.PMID 8360490Read ↗

The high-affinity immunoglobulin-E receptor (FcepsilonRI) is endocytosed by an AP-2/clathrin-independent, dynamin-dependent mechanism.Semantic proximity Read ↗

The first transmembrane region of the beta-chain stabilizes the tetrameric Fc epsilon RI complex.Semantic proximity Read ↗

Immobilization and internalization of mutated IgE receptors in transfected cells.Semantic proximity Read ↗

Surface expression of mutated subunits of the high affinity mast cell receptor for IgE.Semantic proximity Read ↗

Two distinct regions of FC gamma RI initiate separate signalling pathways involved in endocytosis and phagocytosis.Semantic proximity Read ↗

Structure of the Fc fragment of human IgE bound to its high-affinity receptor Fc epsilonRI alpha.Semantic proximity Read ↗

A Truncated Splice-Variant of the FcεRIβ Receptor Subunit Is Critical for Microtubule Formation and Degranulation in Mast CellsSemantic proximity Read ↗

Attenuation of IgE affinity for FcepsilonRI radically reduces the allergic response in vitro and in vivo.Semantic proximity Read ↗

Exon Skipping of FcεRIβ for Allergic Diseases.Semantic proximity Read ↗

Fc receptor endocytosis is controlled by a cytoplasmic domain determinant that actively prevents coated pit localization.Semantic proximity Read ↗

Characterization and expression of the gene for the human Fc receptor gamma subunit. Definition of a new gene family.Semantic proximity Read ↗

Localization of the Fc epsilon RI binding site to the third constant domain of IgE.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.