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Article

Rho-kinase regulates tissue morphogenesis via non-muscle myosin and LIM-kinase during Drosophila development.

BMC developmental biology - 1 Aug 2006

Verdier Valerie, Guang-Chao-Chen, Settleman Jeffrey

Abstract excerpt

BACKGROUND: The Rho-kinases (ROCKs) are major effector targets of the activated Rho GTPase that have been implicated in many of the Rho-mediated effects on cell shape and movement via their ability to affect acto-myosin contractility. The role of ROCKs in cell shape change and motility suggests a potentially important role for Rho-ROCK signaling in tissue morphogenesis during development. Indeed, in Drosophila, a...

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Identifiers

PMID: 16882341
DOI: 10.1186/1471-213X-6-38
PMCID: PMC1552057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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