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Article

A structural bioinformatics approach to explore the interactions of P53 and BRCA1 gene products on ovarian and breast cancer.

International journal of bioinformatics research and applications - 1 Jan 2011

Parija Satyajeet, Kumar Amit

Abstract excerpt

A vast majority of the ovarian and the breast cancers are sporadic and result from the accumulation of genetic damage. Most preclinical data suggest that women experiencing ovarian cancer are prone to breast cancer and vice versa. Similar domains and similar binding sites often imply similar protein?protein interactions and similar functions. Zinc finger of P53 and Ring finger of BRCA1 are similar domains having...

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Source

Identifiers

PMID: 21441093
DOI: 10.1504/IJBRA.2011.039166

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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