Article
Objective functions.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2014
Doğan Haluk, Otu Hasan H
Abstract excerpt
Multiple sequence alignment involves alignment of more than two sequences and is an NP-complete problem. Therefore, heuristic algorithms that use different criteria to find an approximation to the optimal solution are employed. At the heart of these approaches lie the scoring and objective functions that a given algorithm uses to compare competing solutions in constructing a multiple sequence alignment. These...
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