Article
GWAS signals across the HLA regions: revealing a clue for common etiology underlying infectious tumors and other immunity diseases.
Chinese journal of cancer - 1 Apr 2011
Shugart Yin Yao, Wang Ying, Jia Wei-Hua, Zeng Yi-Xin
Abstract excerpt
Increasing evidence suggests that multiple genes in the human leukocyte antigen(HLA) regions play an important role in development of cancers and immunity disorders. However, the biological mechanisms of the HLA associations are not well understood. We recently conducted a survey of all genome-wide association studies (GWAS) with significant findings in the HLA regions and concluded that diseases such as cancer...
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