Article
Immunogenetics and infectious diseases: special reference to the mayor histocompatibility complex.
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Apr 2006
Alves Crésio, Souza Thaisa, Meyer Isadora, Toralles Maria Betânia P, Brites Carlos
Abstract excerpt
Many studies have tried to identify genetic markers for infectious diseases, some of them have focused on human leukocyte antigens (HLA). The products of HLA genes interact with surface-specific receptors of T lymphocytes, resulting in activation of the host's immune response. Association of bacterial, viral, parasitic and fungal infections with the host's HLA has been widely investigated. The type and strength...
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