Article
Pituitary tumor transforming gene-1 haplotypes and risk of pituitary adenoma: a case-control study.
BMC medical genetics - 25 Mar 2011
Chen Shuai, Xiao Lan, Liu Zhixiong, Liu Jinfang, Liu Yunsheng
Abstract excerpt
BACKGROUND: It has been suggested that pituitary adenoma results from accumulation of multiple genetic and/or epigenetic aberrations, which may be identified through association studies. As pituitary tumor transforming gene-1 (PTTG1)/securin plays a critical role in promoting genomic instability in pituitary neoplasia, the present study explored the association of PTTG1 haplotypes with the risk of pituitary...
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