Article
Common variants at 10p12.31, 10q21.1 and 13q12.13 are associated with sporadic pituitary adenoma.
Nature genetics - 1 Jul 2015
Ye Zhao, Li Zhiqiang, Wang Yongfei, Mao Ying, Shen Ming, Zhang Qilin, Li Shiqi, Zhou Liangfu, Shou Xuefei, Chen Jianhua, Song Zhijian, Ma Zengyi, Zhang Zhaoyun, Li Yiming, Ye Hongying, Huang Chuanxin, Wang Tao, He Wenqiang, Zhang Yichao, Xie Rong, Qiao Nidan, Qiu Huijia, Huang Shan, Wang Meng, Shen Jiawei, Wen Zujia, Li Wenjin, Liu Ke, Zhou Juan, Wang Lin, Ji Jue, Wang Yin, Chen Hong, Cheng Haixia, Shi Zhifeng, Zhu Yuqian, Geng Daoying, Yao Zhenwei, Tang Weijun, Lu Bin, Pan Li, Zhang Yi, Bao Weimin, Wu Jinsong, Zheng Kang, Shi Yongyong, Zhao Yao
Abstract excerpt
Pituitary adenoma is one of the most common intracranial neoplasms, and its genetic basis remains largely unknown. To identify genetic susceptibility loci for sporadic pituitary adenoma, we performed a three-stage genome-wide association study (GWAS) in the Han Chinese population. We first analyzed genome-wide SNP data in 771 pituitary adenoma cases and 2,788 controls and then carried forward the promising...
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