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Article

SIRT1 (rs3740051) role in pituitary adenoma development.

BMC medical genetics - 20 Nov 2019

Liutkeviciene Rasa, Vilkeviciute Alvita, Morkunaite Greta, Glebauskiene Brigita, Kriauciuniene Loresa

Abstract excerpt

BACKGROUND: Our purpose was to determine if SIRT1 (rs4746720, rs3740051) genotypes have an influence on the development of pituitary adenoma (PA). METHODS: The study group included 142 patients with pituitary adenoma (PA) and the control group consisted of 826 healthy people. The genotyping of SIRT1 (rs4746720, rs3740051) was carried out using the real-time polymerase chain reaction method. RESULTS: Statistically...

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Identifiers

PMID: 31747893
DOI: 10.1186/s12881-019-0892-x
PMCID: PMC6868839

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