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Article

LRRC4 haplotypes are associated with pituitary adenoma in a Chinese population.

Medical oncology (Northwood, London, England) - 1 Apr 2014

Xiao Lan, Tu Chaofeng, Chen Shuai, Yu Zhibin, Lei Qianqian, Wang Zeyou, Xu Gang, Wu Minghua, Li Guiyuan

Abstract excerpt

Pituitary adenoma results from accumulation of multiple genetic and/or epigenetic aberrations such as GNAS, MEN1, CNC, and FIPA. LRRC4 is relatively tissue-specific expressed gene in the normal brain and downregulated expression in glioma (87.5%), meningioma (80.9%), and pituitary adenoma (85.5%). It has been suggested that the aberrant expression of LRRC4 contributes to tumorigenesis in glioma. However, little...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24563334
DOI: 10.1007/s12032-014-0888-5

Genes

AGT
GNAS
MEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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