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Article

Enteric adenovirus 41 (Tak) requires low serum for growth in human primary cells.

Virology - 1 Sept 1990

Pieniazek D, Pieniazek N J, Macejak D, Luftig R B

Abstract excerpt

It had been postulated that due to lack of growth of enteric adenovirus 41 (Ad41) on human primary cells and its growth on Graham-293 cells there was a defect in the Ad41 E1A region. However, we found as a result of careful evaluation of Ad41 growth on several primary cell lines (HEK, WI-38, or Detroit 551) that efficient viral multiplication is possible if the serum concentration in the medium used postinfection...

Topics

Adenovirus Early Proteins
Adenovirus Infections, Human
Adenoviruses, Human
Blood
Cells, Cultured
DNA Replication
DNA, Viral
HeLa Cells
Heat-Shock Proteins
Humans
Mutation
Oncogene Proteins, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Virus Replication

Source

Identifiers

PMID: 2143875
DOI: 10.1016/0042-6822(90)90380-a

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2143875-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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