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Article

Rif1 supports the function of the CST complex in yeast telomere capping.

PLoS genetics - 1 Mar 2011

Anbalagan Savani, Bonetti Diego, Lucchini Giovanna, Longhese Maria Pia

Abstract excerpt

Telomere integrity in budding yeast depends on the CST (Cdc13-Stn1-Ten1) and shelterin-like (Rap1-Rif1-Rif2) complexes, which are thought to act independently from each other. Here we show that a specific functional interaction indeed exists among components of the two complexes. In particular, unlike RIF2 deletion, the lack of Rif1 is lethal for stn1ΔC cells and causes a dramatic reduction in viability of...

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Identifiers

PMID: 21437267
DOI: 10.1371/journal.pgen.1002024
PMCID: PMC3060071

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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