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Article

Comparative analysis of germline and somatic microlesion mutational spectra in 17 human tumor suppressor genes.

Human mutation - 1 Jun 2011

Ivanov Dobril, Hamby Stephen E, Stenson Peter D, Phillips Andrew D, Kehrer-Sawatzki Hildegard, Cooper David N, Chuzhanova Nadia

Abstract excerpt

Mutations associated with tumorigenesis may either arise somatically or can be inherited through the germline. We performed a comparison of somatic, germline, shared (found in both soma and germline) and somatic recurrent mutational spectra for 17 human tumor suppressor genes, which focused upon missense single base-pair substitutions and microdeletions/microinsertions. Somatic and germline mutational spectra...

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Identifiers

PMID: 21432943
DOI: 10.1002/humu.21483

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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