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Article

Loss of heterozygosity of M6P/IGF2R gene is an early event in the development of prostate cancer.

Prostate cancer and prostatic diseases - 1 Jan 2006

Hu C K, McCall S, Madden J, Huang H, Clough R, Jirtle R L, Anscher M S

Abstract excerpt

BACKGROUND: The genetic events leading to initiation and/or progression of prostate cancer are not well characterized. The gene coding for the mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) has recently been identified as a tumor suppressor in several types of cancer. The p...

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PMID: 16304558
DOI: 10.1038/sj.pcan.4500842

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16304558-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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