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Article

Deregulation of an imprinted gene network in prostate cancer

10 Feb 2014

Abstract excerpt

Multiple epigenetic alterations contribute to prostate cancer progression by deregulating gene expression. Epigenetic mechanisms, especially differential DNA methylation at imprinting control regions (termed DMRs), normally ensure the exclusive expression of imprinted genes from one specific parental allele. We therefore wondered to which extent imprinted genes become deregulated in prostate cancer and, if so,...

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Share to Epigenetics and DNA Methylation
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PMID: 24513574
DOI: 10.4161/epi.28006

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