Article
Epigenetic susceptibility factors for prostate cancer with aging.
The Prostate - 1 Dec 2013
Damaschke N A, Yang B, Bhusari S, Svaren J P, Jarrard D F
Abstract excerpt
BACKGROUND: Increasing age is a significant risk factor for prostate cancer. The prostate is exposed to environmental and endogenous stress that may underlie this remarkable incidence. DNA methylation, genomic imprinting, and histone modifications are examples of epigenetic factors known to undergo change in the aging and cancerous prostate. In this review we examine the data linking epigenetic alterations in the...
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