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HIV-1 replicative fitness in elite controllers

24 Mar 2011

Abstract excerpt

PURPOSE OF REVIEW: Differential rates of disease progression are obviously multifactorial, but the virulence of the actual infecting virus is most frequently ignored as potential source of slow or rapid disease progression. In this review, the argument will be made that nearly all elite suppressors are infected by weak HIV-1 strain (in terms of replicative capacity). Whether this poor virus replication is the...

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PMID: 21430530
DOI: 10.1097/coh.0b013e3283454cf5

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