Article
Impaired human immunodeficiency virus type 1 replicative fitness in atypical viremic non-progressor individuals.
AIDS research and therapy - 1 Jan 2017
Weber Jan, Gibson Richard M, Sácká Lenka, Strunin Dmytro, Hodek Jan, Weberová Jitka, Pávová Marcela, Alouani David J, Asaad Robert, Rodriguez Benigno, Lederman Michael M, Quiñones-Mateu Miguel E
Abstract excerpt
BACKGROUND: Progression rates from initial HIV-1 infection to advanced AIDS vary significantly among infected individuals. A distinct subgroup of HIV-1-infected individuals-termed viremic non-progressors (VNP) or controllers-do not seem to progress to AIDS, maintaining high CD4+ T cell counts despite high levels of viremia for many years. Several studies have evaluated multiple host factors, including immune...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.