Infrequent Recovery of HIV from but Robust Exogenous Infection of Activated CD4⁺T Cells in HIV Elite Controllers

Abstract excerpt

BACKGROUND. Human immunodeficiency virus (HIV) elite controllers are able to control infection with HIV-1 spontaneously to undetectable levels in the absence of antiretroviral therapy, but the mechanisms leading to this phenotype are poorly understood. Although low frequencies of HIV-infected peripheral CD4(+) T cells have been reported in this group, it remains unclear to what extent these are due to viral...

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