Article
Alu distribution and mutation types of cancer genes.
BMC genomics - 23 Mar 2011
Zhang Wensheng, Edwards Andrea, Fan Wei, Deininger Prescott, Zhang Kun
Abstract excerpt
BACKGROUND: Alu elements are the most abundant retrotransposable elements comprising ~11% of the human genome. Many studies have highlighted the role that Alu elements have in genetic instability and how their contribution to the assortment of mutagenic events can lead to cancer. As of yet, little has been done to quantitatively assess the association between Alu distribution and genes that are causally...
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