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Article

Circulating Alu Elements as Biomarkers for Radiation-Induced Toxicity in Cancer.

Genetic testing and molecular biomarkers - 1 May 2026

Patel Mansi, Jyotishi Charmi, Prajapati Suresh, Gupta Reeshu

Abstract excerpt

Radiation therapy is a key treatment for many cancers, but patient responses vary due to differences in genomic stability and DNA repair capacity. Increasing evidence highlights the role of Alu elements, the most abundant short interspersed nuclear elements in the human genome, as regulators of cellular stress responses. This review summarizes current knowledge on Alu biology, including their structure,...

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Alu Elements
DNA Damage
DNA Methylation
DNA Repair
Genomic Instability

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microsatellite Instability

Radiation Injuries

Radiation, Ionizing

Source

Identifiers

PMID: 41995355
DOI: 10.1177/19450265261444622

Genes

BRCA2
TP53

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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