Article
Nonrandom distribution of alu elements in genes of various functional categories: insight from analysis of human chromosomes 21 and 22.
Molecular biology and evolution - 1 Sept 2003
Grover Deepak, Majumder Partha P, B Rao Chandrika, Brahmachari Samir K, Mukerji Mitali
Abstract excerpt
The first draft of the human genome has revealed enormous variability in the global distribution of Alu repeat elements. There are regions such as the four homeobox gene clusters, which are nearly devoid of these repeats that contrast with repeat dense regions in other transcriptionally active regions of the genome. Our analysis of the completely sequenced chromosomes 21 and 22 revealed a striking bias in Alu...
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