Article
The role of Bacteroides fragilis RecQ DNA helicases in cell survival after metronidazole exposure.
FEMS microbiology letters - 1 Jun 2011
Paul Lynthia, Patrick Sheila, Nord Carl Erik, Abratt Valerie
Abstract excerpt
The inactivation of Bacteroides fragilis genes encoding putative RecQ helicases recQ1, recQ2 and recQ3 (ORFs BF638R_3282, BF638R_3781, BF638R_3932) was used to determine whether these proteins are involved in cell survival following metronidazole exposure. The effects of the mutations on growth, cellular morphology and DNA integrity were also evaluated. Mutations in the RecQ DNA helicases caused increased...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
