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Article

Role of the Escherichia coli RecQ DNA helicase in SOS signaling and genome stabilization at stalled replication forks.

Genes & development - 1 Aug 2004

Hishida Takashi, Han Yong-Woon, Shibata Tatsuya, Kubota Yoshino, Ishino Yoshizumi, Iwasaki Hiroshi, Shinagawa Hideo

Abstract excerpt

The RecQ protein family is a highly conserved group of DNA helicases that play roles in maintaining genomic stability. In this study, we present biochemical and genetic evidence that Escherichia coli RecQ processes stalled replication forks and participates in SOS signaling. Cells that carry dnaE486, a mutation in the DNA polymerase III alpha-catalytic subunit, induce an RecA-dependent SOS response and become...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 15289460
DOI: 10.1101/gad.1223804
PMCID: PMC517408

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role of the Escherichia coli RecQ DNA helicase in SOS signaling and genome stabilization at stalled replication forks.PMID 15289460Read ↗

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