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Article

TLR3 and RIG-I gene variants: associations with functional effects on receptor expression and responses to measles virus and vaccine in vaccinated infants.

Human immunology - 1 Jun 2012

Clifford Holly D, Yerkovich Stephanie T, Khoo Siew-Kim, Zhang Guicheng, Upham John, Le Souëf Peter N, Richmond Peter, Hayden Catherine M

Abstract excerpt

Measles virus causes severe morbidity and mortality, despite the availability of measles vaccines. Successful defence against viral pathogens requires early recognition of virus-specific patterns by innate receptors like Toll-like receptor (TLR)3 and the RNA helicase, retinoic acid inducible gene...

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Source

Identifiers

PMID: 22504413
DOI: 10.1016/j.humimm.2012.03.004

Genes

TLR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22504413-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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