Article
Identification of two nuclear genes (ATP11, ATP12) required for assembly of the yeast F1-ATPase.
Proceedings of the National Academy of Sciences of the United States of America - 1 Jul 1990
Ackerman S H, Tzagoloff A
Abstract excerpt
Nuclear respiratory-deficient mutants of Saccharomyces cerevisiae (pet mutants) have been screened for defects in the mitochondrial ATPase. Mutants in two complementation groups were found to have 10% or less of wild-type ATPase activity. The two wild-type nuclear genes defined by the mutants hav...
Topics
- Cell Nucleus
- DNA, Fungal
- Genes, Fungal
- Genetic Complementation Test
- Genotype
- Macromolecular Substances
- Mitochondria
- Mutation
- Nucleic Acid Hybridization
- Protein Processing, Post-Translational
- Proton-Translocating ATPases
- Saccharomyces cerevisiae
- Submitochondrial Particles
- Transcription, Genetic