Article
Identification of functional domains in Atp11p. Protein required for assembly of the mitochondrial F1-ATPase in yeast.
The Journal of biological chemistry - 1 Mar 1996
Wang Z G, Ackerman S H
Abstract excerpt
The Atp11p protein of Saccharomyces cerevisiae is required for proper assembly of the F1 component of the mitochondrial ATP synthase. The mutant atp11 genes were cloned and sequenced from 12 yeast strains, which are respiratory-deficient due to a defect in Atp11p function. Four of the mutations mapped to the mitochondrial targeting domain (amino-terminal 39 amino acids) of Atp11p. All the genetic lesions found in...
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