Article
Characterization of ATP12, a yeast nuclear gene required for the assembly of the mitochondrial F1-ATPase.
The Journal of biological chemistry - 25 Apr 1991
Bowman S, Ackerman S H, Griffiths D E, Tzagoloff A
Abstract excerpt
Mitochondrial F1-ATPase is an oligomeric enzyme composed of five distinct subunit polypeptides. The alpha and beta subunits make up the bulk of protein mass of F1. In Saccharomyces cerevisiae both subunits are synthesized as precursors with amino-terminal targeting signals that are removed upon translocation of the proteins to the matrix compartment. Recently, two different complementation groups (G13, G57),...
Topics
- Amino Acid Sequence
- Base Sequence
- Blotting, Western
- Cloning, Molecular
- Electrophoresis, Polyacrylamide Gel
- Mitochondria
- Molecular Sequence Data
- Mutation
- Proton-Translocating ATPases
- Restriction Mapping