Article
ATP10, a yeast nuclear gene required for the assembly of the mitochondrial F1-F0 complex.
The Journal of biological chemistry - 15 Jun 1990
Ackerman S H, Tzagoloff A
Abstract excerpt
A yeast nuclear gene (ATP10) is reported whose product is essential for the assembly of a functional mitochondrial ATPase complex. Mutations in ATP10 induce a loss of rutamycin sensitivity in the mitochondrial ATPase but do not affect respiratory enzymes. This phenotype has been correlated with a defect in the F0 sector of the ATPase. The wild type ATP10 gene has been cloned by transformation of an atp 10 mutant...
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