Article
Cytolytic activity of intestinal intraepithelial lymphocytes in germ-free mice is strain dependent and determined by T cells expressing gamma delta T-cell antigen receptors.
Proceedings of the National Academy of Sciences of the United States of America - 15 Sept 1993
Kawaguchi M, Nanno M, Umesaki Y, Matsumoto S, Okada Y, Cai Z, Shimamura T, Matsuoka Y, Ohwaki M, Ishikawa H
Abstract excerpt
We have compared the cytolytic activities and the cellular compositions of the intestinal intraepithelial lymphocyte (i-IEL) populations in three different combinations of conventional (CV) and germ-free (GF) mice. Cytolytic activity of i-IELs expressing gamma delta T-cell antigen receptors (TCRs...
Topics
- Animals
- Antibodies, Monoclonal
- CD3 Complex
- Cells, Cultured
- Cytotoxicity, Immunologic
- Epithelium
- Fluorescent Antibody Technique
- Intestines
- Kinetics
- Mast-Cell Sarcoma
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL