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Article

Protection of the intestinal mucosa by intraepithelial gamma delta T cells.

Proceedings of the National Academy of Sciences of the United States of America - 29 Oct 2002

Chen Yaping, Chou Kevin, Fuchs Elaine, Havran Wendy L, Boismenu Richard

Abstract excerpt

gammadelta intraepithelial T lymphocytes (IEL) represent a major T cell population within the intestine of unclear functional relevance. The role of intestinal gammadelta IEL was evaluated in the dextran sodium sulfate (DSS) induced mouse colitis model system. Large numbers of gammadelta T cells, but not alphabeta T cells, were localized at sites of DSS-induced epithelial cell damage. gammadelta IEL in DSS...

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Share to Cell Division
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epithelial Cells

Share to Fibroblast Growth Factors

Share to Intestinal Mucosa

Share to Receptors, Antigen, T-Cell, gamma-delta

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Source

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Identifiers

PMID: 12376619
DOI: 10.1073/pnas.212290499
PMCID: PMC137885

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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