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Article

Analysis of the 8.1 ancestral MHC haplotype in severe, pneumonia-related sepsis.

Clinical immunology (Orlando, Fla.) - 1 Jun 2011

Aladzsity István, Madách Krisztina, Szilágyi Agnes, Gál János, Pénzes István, Prohászka Zoltán, Fust George

Abstract excerpt

The most frequent Caucasian MHC haplotype, AH8.1 - associated with numerous immunopathological differences and certain autoimmune diseases - was recently linked to the delayed onset of bacterial colonization in cystic fibrosis. Based on this observation, we hypothesized that the carriers of AH8.1 have lower risk for a worse outcome in sepsis. AH8.1 carrier state was determined in 207 Caucasian patients with...

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Identifiers

PMID: 21414845
DOI: 10.1016/j.clim.2011.02.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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