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Article

Identifying a major locus that regulates spontaneous arthritis in IL-1ra-deficient mice and analysis of potential candidates.

Genetics research - 1 Apr 2011

Jiao Yan, Jiao Feng, Yan Jian, Xiong Qing, Shriner Daniel, Hasty Karen, Stuart John, Gu Weikuan

Abstract excerpt

To identify genetic loci that regulate spontaneous arthritis in interleukin-1 receptor antagonist (IL-1ra)-deficient mice, an F2 population was created from a cross between Balb/c IL-1ra-deficient mice and DBA/1 IL-1ra-deficient mice. Spontaneous arthritis in the F2 population was examined and recorded. Genotypes of those F2 mice were determined using microsatellite markers. Quantitative trail locus (QTL)...

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Source

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Identifiers

PMID: 21414240
DOI: 10.1017/S0016672310000704
PMCID: PMC3245888

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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