Article
hOGG1 Ser326Cys polymorphism and risk of hepatocellular carcinoma among Japanese.
Journal of epidemiology - 1 Nov 2006
Sakamoto Tatsuhiko, Higaki Yasuki, Hara Megumi, Ichiba Masayoshi, Horita Mikako, Mizuta Toshihiko, Eguchi Yuichiro, Yasutake Tsutomu, Ozaki Iwata, Yamamoto Kyosuke, Onohara Shingo, Kawazoe Seiji, Shigematsu Hirohisa, Koizumi Shunzo, Tanaka Keitaro
Abstract excerpt
BACKGROUND: The Ser326Cys polymorphism in human oxoguanine glycosylase 1 (hOGG1), which is involved in the repair of 8-hydroxy-2-deoxyguanine in oxidatively damaged DNA, has been associated with susceptibility to certain cancers, but has not been examined in causation of hepatocellular carcinoma...
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