Article
The contribution of a 9p21.3 variant, a KIF6 variant, and C-reactive protein to predicting risk of myocardial infarction in a prospective study.
BMC cardiovascular disorders - 15 Mar 2011
Shiffman Dov, O'Meara Ellen S, Rowland Charles M, Louie Judy Z, Cushman Mary, Tracy Russell P, Devlin James J, Psaty Bruce M
Abstract excerpt
BACKGROUND: Genetic risk factors might improve prediction of coronary events. Several variants at chromosome 9p21.3 have been widely reported to be associated with coronary heart disease (CHD) in prospective and case-control studies. A variant of KIF6 (719Arg) has also been reported to be associated with increased risk of CHD in large prospective studies, but not in case-control studies. We asked whether the...
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