Article
Investigation of KIF6 Trp719Arg in a case-control study of coronary artery disease in Western Indians.
Genetic testing and molecular biomarkers - 1 Dec 2011
Bhanushali Aparna A, Contractor Aashish, Shah Vijay T, Das Bibhu R
Abstract excerpt
BACKGROUND: A single-nucleotide polymorphism Trp719Arg (rs20455T>C) in the kinesin-like protein 6 (KIF6), which is a protein involved in intracellular transport, has been shown to predict increased coronary artery disease (CAD) risk and event reduction during statin therapy. AIM: In the current study, we have evaluated the association of the variant Trp719Arg with CAD/non fatal myocardial infarction (MI) in...
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