Article
Transport and secretion of truncated T cell receptor beta-chain occurs in the absence of association with CD3.
The Journal of biological chemistry - 5 Jun 1990
Gascoigne N R
Abstract excerpt
The T cell receptor (TCR) beta-chain is produced in the endoplasmic reticulum where it associates with the TCR alpha-chain and the members of the CD3 complex to form the complete receptor. When the other chains of the complex are not available, the beta-chain is rapidly degraded within the endoplasmic reticulum. When incomplete TCR.CD3 complexes are formed, they are transported through the Golgi apparatus and...
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